CORNEA
Castroviejo Lecture: My Superpower! How High-Resolution Imaging Has Changed My Practice of Ocular Surface Oncology
Presented by Carol L. Karp, MD
When: Sunday, 8:47-9:15 a.m., during Sym21, I Can See: The Role of Anterior Segment Imaging
Where: Grand Ballroom S100ab
“High-resolution anterior segment optical coherence tomography (HR-OCT) has emerged as a powerful and reliable tool for the diagnosis of various anterior segment pathologies. Images of high axial resolution have allowed physicians to better visualize with increasing detail the tear film, corneal layers, corneal/scleral junction, anterior chamber angle, and various layer interfaces.
“In particular, HR-OCT has revolutionized our ability to diagnose and differentiate between various ocular surface lesions, providing morphological information about the lesion of interest to help guide diagnosis and management. Ocular surface tumors, such as ocular surface squamous neoplasia, conjunctival melanoma, conjunctival lymphoma, conjunctival amyloidosis, and benign lesions such as pingueculae and pterygia have classic HR-OCT findings, providing an ‘optical biopsy’ of various ocular surface lesions. I like to joke that the HR-OCT gives me ‘superpowers’ to evaluate what is happening on the ocular surface in a way that compliments and supersedes the clinical examination.
“I plan to share my step-by-step approach to acquiring and interpreting HR-OCT images in my 2022 Castroviejo lecture. I hope this will allow you to best help your patients with ocular surface lesions.”
I Can See: The Role of Anterior Segment Imaging (8:00-9:15 a.m.) is cosponsored by the Cornea Society.
PEDIATRIC OPHTHALMOLOGY
Marshall M. Parks Lecture: ROP: From “Plus” Disease to “Plus” Contributions!
Presented by Susan H. Day, MD
When: Sunday, 8:50-9:15 a.m., during Sym20, Retinopathy of Prematurity
Where: Room E450
“In half a century, retinopathy of prematurity (ROP) is clearly one example of how scientific advances occur: the ability to ask the right question; interdisciplinary research; enhanced technology; standardization of clinical features and language; QALY scales connoting value; NICU regulations requiring skilled eye examiners; and international awareness and education. The physicians’ roles have been essential along every step of this journey. What remaining challenges deserve our attention as our careers mature?
“Retinopathy of prematurity is a perfect model for another ‘ROP’: responsibility, opportunity, and progress. The horizons of how we might help our patients are limitless, as are all ophthalmologists’ potential, regardless of expertise, avocational interests, and demographic identities. As retirement ensues, what new chapters might unfold for us to continue to make a positive difference? How might we collectively apply our unique experience in the science and art of medicine to enrich the lives of others and of self?”
Retinopathy of Prematurity (8:00-9:15 a.m.) is cosponsored by the American Association of Pediatric Ophthalmology and Strabismus.
UVEITIS AND IMMUNOLOGY
C. Stephen and Frances Foster Lecture on Uveitis and Immunology: Syphilis: Past, Present and Future
Presented by Debra A. Goldstein, MD
When: Sunday, 11:30 a.m.-12:30 p.m., during Sym34, C. Stephen and Frances Foster Lecture on Uveitis and Immunology
Where: Room S406a
The C. Stephen and Frances Foster Lecture in Ocular Immunology recognizes the groundbreaking work of C. Stephen Foster, MD, FACS, FACR, founder and president of Massachusetts Eye and Research Institution. Each year, the Foster Lecture is presented by an eminent authority on a clinical, research, or therapeutic subject related to ocular inflammatory disease.
This year’s speaker is Debra A. Goldstein, MD, director of uveitis in the department of ophthalmology and Magerstadt Professor of Ophthalmology at the Northwestern University Feinberg School of Medicine in Chicago.
C. Stephen and Frances Foster Lecture on Uveitis and Immunology (11:30 a.m.-12:30 p.m.).
OCULOPLASTICS
Wendell L. Hughes Lecture: Multi-Disciplinary Management of Eyelid and Orbital Cancers in the Era of Biologics and Immunotherapy
Presented by Bita Esmaeli, MD
When: Sunday, 11:31-11:56 a.m., during Sym30, I’ve Been Waiting for Someone to Ask: Tips to Improving Your Oculofacial Plastic Clinic Exam & Surgical Outcomes
Where: Room E450
“What an honor to give the lecture that is named after a legend in ophthalmic plastic surgery, Dr. Wendell Hughes. In more than 25 years of practice as an oncologic ophthalmic plastic surgeon at a tertiary cancer hospital in the United States, I have witnessed firsthand the very positive impact the Hughes procedure has had on my patients’ well-being and quality of life.
“I have also seen the revolutionary discovery of biologics and immunotherapy-based cancer drugs and how they have enhanced the surgical care that I can deliver to cancer patients with challenging locally advanced disease. In my talk, I will show a potpourri of interesting periocular and orbital cancer cases, both common and rare, that have benefited from a multidisciplinary individualized treatment approach. I will highlight practical information such as patient selection, expected outcomes, and surgical pearls for achieving the best functional and aesthetic results.”
I’ve Been Waiting for Someone to Ask: Tips to Improving Your Oculofacial Plastic Clinic Exam & Surgical Outcomes (11:30 a.m.-12:45 p.m.) is cosponsored by the American Society of Ophthalmic Plastic and Reconstructive Surgery.
ORGANIZED MEDICINE
Parker Heath Lecture: Thinking About the Future of Medicine
Presented by James L. Madara, MD
When: Sunday, 12:08-12:23 p.m., during Sym32, Innovations in Ophthalmology From Around the World
Where: Room E354
The Parker Heath lecture honors Parker Heath, MD, who was the 54th president of the American Ophthalmic Society and was known as a pioneer in ophthalmic pathology. The Parker Heath lecturer is always a prominent ophthalmologist or other physician who can speak to topics that broadly apply to all of medicine.
Innovations in Ophthalmology From Around the World (11:30 a.m.-12:45 p.m.) is cosponsored by the American Medical Association Ophthalmology Section Council.
NEURO-OPHTHALMOLOGY
William F. Hoyt Lecture: The Superior Colliculus: A Path to Neuro-Ophthalmology
Presented by Steven E. Feldon, MD
When: Sunday, 12:25-12:45 p.m., during Sym31, Vision- and Life-Threatening Signs and Symptoms: Pearls From Neuro-Ophthalmology
Where: Grand Ballroom S100ab
“As an undergraduate student at the University of California, Los Angeles, I had the unique opportunity to do vision research in the lab of Lawrence Kruger, PhD, professor of anatomy. My assignment was to ascertain the topographic projection of the visual field on the superior colliculus of the cat. These studies resulted in my first scientific publication in 1970 and led to my fascination with the neurology of the visual system and to my career as a neuro-ophthalmologist. In this lecture honoring my mentor, William F. Hoyt, I return to that formative stage in my career path to introduce this audience to the extensively studied, but clinically underappreciated, role of the superior colliculus (SC) in health and disease.
“The SC is a laminated dorsal midbrain structure with multiple layers. The superficial layer is dominated by sensory inputs from the retina, and there are projections from the SC to the lateral geniculate, pulvinar, and visual cortex. The deeper layers are primarily associated with the initiation of saccadic eye movements to visual targets. Sensorimotor integration occurs in the intermediate layers.
“The decision to look at or ignore any specific target in the contralateral hemifield may be, at least in part, based upon valences computed by the SC. The computation uses not only visual inputs but also multiple sensory and even emotional inputs. The SC is also involved in basic visual motor interactions, such as maintaining visual fixation with microsaccades, suppressing images during saccadic eye movements, and generating express saccades that are initiated more quickly than volitional saccades. Perhaps unexpectedly, the SC is implicated in esoteric and complex conditions such as ‘blindsight’ and autism.”
Vision- and Life-Threatening Signs and Symptoms: Pearls From Neuro-Ophthalmology (11:30 a.m.-12:45 p.m.) is cosponsored by the North American Neuro-Ophthalmology Society.
REFRACTIVE SURGERY
Barraquer Lecture: Untying the Knot! Reversing the Impact of Refractive Surgery
Presented by Graham Barrett, MD
When: Sunday, 12:30-12:50 p.m., during Sym33, Treatment of Presbyopia
Where: Grand Ballroom S100c
The José I. Barraquer Lecture and Award honors a physician who has made significant contributions in the field of refractive surgery during his or her career. This individual exemplifies the character and scientific dedication of José I. Barraquer, MD—one of the founding fathers of refractive surgery, who innovated both in techniques and instrumentation.
This year’s lecturer, Dr. Barrett, is consultant ophthalmic surgeon at Sir Charles Gairdner Hospital and clinical professor in the University of Western Australia’s Centre for Ophthalmology and Visual Science. Dr. Barrett’s interests include lens prediction formulas, new techniques in cataract and refractive surgery, and IOL design.
Treatment of Presbyopia (11:30 a.m.-12:45 p.m.) is cosponsored by the International Society of Refractive Surgery.
MICROBIOLOGY
Jones-Smolin Lecture: Acanthamoeba Keratitis Treatment; ODAK Phase 3 Trial Outcomes
Presented by John K. Dart, MD
When: Sunday, 2:47-3:10 p.m., during Sym39, Ocular COVID-19: Questions and Answers
Where: Grand Ballroom S100c
“Acanthamoeba keratitis (AK), fittingly for this lecture, was first described in 1975 by Dan Jones, a mentor with whom I studied in 1983-1984. Infectious and inflammatory anterior segment disease has been the focus of my research since then, a time during which AK has become a frequent cause of severe keratitis and one of the most intractable.
“Although an orphan disease, AK is important because in many major economies contact lens use is the principal cause of microbial keratitis, of which AK accounts for about 50% of cases that develop sight loss. This problem led to the introduction, at Moorfields Eye Hospital, in 1992 of the disinfectant PHMB (polyhexanide) as a novel and effective topical antiamoebic.
“I will present the results of a pragmatic and widely applicable phase 3 trial, the last work package of a series that has included formulation, safety, and tolerability studies, supported by an EU grant and sponsored by SiFi pharmaceuticals and designed to provide a licensed AK treatment. I will present not only the results of the trial, which has provided impressive medical cure rates, but also an evaluation of the protocol that was used—and the evidence that a treatment delivery protocol can be as important as drug efficacy.”
Ocular COVID-19: Questions and Answers (2:00-3:15 p.m.) is cosponsored by the Ocular Microbiology and Immunology Group.
PATHOLOGY/ONCOLOGY
Zimmerman Lecture: Glaucoma Insights: An Ophthalmic Pathologist’s Perspective
Presented by Deepak P. Edward, MD, FACS, FARVO
When: Sunday, 2:53-3:15 p.m., during Sym40, An Update on Efforts to Improve Mortality in Ocular Cancers
Where: Room E450
“The pathophysiology of the different forms of glaucoma is complex and so are the effects of treatment for the disorder. This lecture will include an ophthalmic pathologist/glaucoma specialist’s journey studying the pathology of congenital glaucoma and other glaucomas, and it will also review immunohistopathologic changes in the optic nerve head in glaucoma. The presentation will discuss clinical-pathologic correlations of the trabeculectomy bleb and molecular pathology of the capsules from glaucoma shunt surgery, and how pathologic studies can provide insight in modifying surgery to improve surgical outcomes.”
An Update on Efforts to Improve Mortality in Ocular Cancers (2:00-3:15 p.m.) is cosponsored by the American Association of Ocular Oncology and Pathology.
CORNEA
Whitney G. Sampson Lecture: Optical Considerations for Presbyopia
Presented by Damien Gatinel, MD
When: Sunday, 4:35-4:50 p.m., during Sym43, New Options for Near Vision: Emerging Treatments for Presbyopia Correction
Where: Grand Ballroom S100c
This lecture is named for Whitney G. Sampson, MD (Oct. 2, 1932-July 18, 2000), who distinguished himself during a time of scientific progress and socioeconomic change. The lecture takes place during the symposium that is cosponsored by the Eye and Contact Lens Association.
This year’s lecturer, Damien Gatinel, MD, is head of the anterior and refractive surgery department of the Rothschild Foundation, Paris, France.
New Options for Near Vision: Emerging Treatments for Presbyopia Correction (3:45-5:00 p.m.) is cosponsored by the Eye and Contact Lens Association.
OCULOPLASTICS/PROSTHETICS
Ruedemann Lecture: Protecting the Inferior Cul-de-Sac
Presented by Kenneth V. Cahill, MD, FACS
When: Sunday, 4:36-5:00 p.m., during Sym44, Prosthetic and Surgical Management of Congenital Anophthalmia and Microphthalmia
Where: Room E350
“Old ideas, new ideas, and forgotten ideas can be used to help maintain a healthy, functional, and cosmetically pleasing socket. Achieving this goal requires the collaboration of patients, surgeons, and ocularists throughout the process, starting at the time of surgery, continuing with the fitting and maintenance of the prosthesis, and as changes occur. We will analyze this process with attention to the inferior conjunctival cul-de-sac to see if there are improvements we can make for the betterment of our patients.”
Prosthetic and Surgical Management of Congenital Anophthalmia and Microphthalmia (3:45-5:00 p.m.) is cosponsored by the American Society of Ocularists.
This content is excerpted from the Sunday/Monday edition of AAO 2022 News, the newspaper distributed at the convention center.
Read more news about Subspecialty Day and AAO 2022.