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    Can You Guess December's Mystery Condition?

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    Make your diagnosis in the comments, and look for the answer in next month’s Blink.

    December 2020 Blink


    Last Month’s Blink

    Apocrine Hidrocystoma

    Written by Mike Rosco, MD, and Rona Z. Silkiss, MD, FACS, California Pacific Medical Center, San Francisco. Photo by Rona Z. Silkiss, MD, FACS.

    November 2020 Blink

    A 23-year-old woman presented with a 10-month history of an enlarging mass on her left eye. Slit-lamp exam revealed a well-circumscribed 1- × 1.2-cm spherical cyst of the left superotemporal bulbar conjunctiva upon inferomedial gaze (Fig. 1). The patient requested removal of the lesion as it was irritating, cos­metically distracting, and leading to an obvious fullness of the upper eyelid (Fig. 2). Surgical exci­sion was performed with narrow margins. Biopsy revealed an apocrine cell-lined cystic structure representing an apocrine hidrocystoma (Fig. 3).

    Apocrine hidrocystomas are benign, well-de­fined, dome-shaped, cystic nodules with a smooth exterior. They are characterized by a double epithelial lining and an outer myoepithelial layer. Ocular apocrine hidrocystomas originate from the blocked excretion of the glands of Moll. Al­though usually found on the lid margin, apocrine hidrocystoma located on the conjunctiva has been documented in a few cases.

    Predominantly seen in adults between the ages of 30 and 70, these formations are equally prev­alent in men and women, and there is no ethnic preponderance.1


    1 Boyun K, Nam K. Int J Ophthalmol. 2012;5(2):247-248.

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