• Genetics of Pigmentary Glaucoma

    Written By: Jean Shaw
    Selected and Reviewed By: Neil M. Bressler, MD, and Deputy Editors

    Despite evidence of familial aggregation, the sporadic nature of pigmentary glaucoma (PG) and its status as a relatively rare condition have stymied research on heritability. Simcoe et al. set out to elucidate the genetics of PG by calculating its single-nucleotide polymorphism (SNP) heritability and identifying other genetic associations. They found a possible genetic component and shared genetic risks with iris pigmentation and myopia.