Medication Adherence and Visual Field Progression in CIGTS
The Collaborative Initial Glaucoma Treatment Study (CIGTS) compared the effect of initial treatment with topical medications to that of trabeculectomy in 607 patients with newly diagnosed glaucoma. Of these, 307 were randomized to the medication arm of the study and underwent regular assessment of their medication adherence and disease progression. Newman-Casey et al. reported long-term data on these patients; they found a statistically and clinically significant association between medication nonadherence and visual field (VF) loss.