In this roundtable discussion, veterans of global ophthalmology share tips about working in developing countries and underserved areas, from finding mentors to securing sources of funding. They candidly reveal the challenges of balancing home life with work when travelling abroad, and how to handle disappointment when reality does not match one's expectations. This course, developed through a collaboration between the Academy and the Bloomberg School of Public Health at Johns Hopkins University, is part of the Academy's Global Ophthalmology (GO) Guide.