Acute retinal necrosis (ARN). A, Wide-field fundus photograph reveals areas of retinal necrosis manifesting as white areas and hemorrhage (arrow) in the periphery. The hazy appearance is due to vitritis. B, Photomicrograph from a different patient reveals full-thickness necrosis of the retina (black bracket), identified by remaining photoreceptor outer segments (asterisk) and RPE cells (arrowhead). Acute and chronic granulomatous inflammation is present below Bruch membrane (red bracket). Neutrophils, epithelioid histiocytes, lymphocytes, and plasma cells are present with a zonal arrangement from top to bottom.