Iris morphology in aniridia in 2 patients with documented PAX6 mutations. A, An eye with aniridia with no iris visible on slit-lamp biomicroscopy, exposing zonules and lens edge. B, An eye with aniridia in which remnants of rudimentary, hypoplastic iris tissue are present. Peripheral aniridic keratopathy, a classic finding in aniridia, is also present.