A, Early-phase fluorescein angiogram of a patient with central serous retinopathy. The yellow arrows outline the area of serous retinal detachment. In the inferotemporal aspect of the serous retinal detachment, there is early minimal hyperfluorescence, with diffuse leakage in late views (B). C, Corresponding optical coherence tomogram illustrating the subretinal fluid accumulation (orange arrow). Accumulation of deposits on the outer surface of the photoreceptors can be seen. This material is thought to represent shed photoreceptor outer segments or fibrin. The green arrow and line on the infrared reflectance imaging shows the scan location of the OCT image.