Choroidal nevi, clinical appearance. The lesion is generally thinner than 2 mm and variably brown. A, Small nevi lack retinal pigment epithelial (RPE) changes. B, Large nevi usually exhibit RPE changes (note the drusen [arrow] and focal RPE hyperplasia [arrowhead]) and C, may show tracks (between arrowheads) revealing past leakage. D, Some nevi display orange pigment (arrows) and are associated with subretinal fluid (asterisk). E, Congenital ocular melanocytosis produces a diffuse nevus–like appearance. F, Melanocytoma, also known as magnocellular nevus, of the optic nerve head. All lesions were followed for several years without evidence of growth.