Cuticular drusen. a. Cuticular drusen are distributed in clusters that can coalesce into larger soft drusen centrally. b. They can be accompanied by vitelliform detachments. c, d. Additional imaging of the patient in (b) shows that these drusen are hyperfluorescent on fluorescein angiography (c) and hypoautofluorescent on fundus autofluorescence (d) with the vitelliform material appearing fluorescent with both modalities. e. Optical coherence tomography demonstrates conical subretinal pigment epithelium elevations with central drusenoid pigment epithelial detachments that coalesce centrally.