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    Fluorescein dye disappearance. Easiest and most common, place fluorescein drops in each eye, Wait five minutes, Objectively grade remaining fluorescein. If it’s normal, a scant amount of fluorescein remains. If it’s abnormal, there is a pooling of fluorescein, asymmetric clearance of dye. Finally, if it is grossly abnormal = fluorescein runs down cheek.