• Part a courtesy of David Sarraf, MD.
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    Hydroxychloroquine maculopathy. a. Early hydroxychloroquine maculopathy. There is a parafoveal ring of hyperautofluorescence (green arrows). b. Hydroxychloroquine maculopathy with atrophy. There is a bull’s-eye pattern of hypoautofluorescence (yellow arrows) corresponding to parafoveal atrophy on the optical coherence tomography (OCT) B-scan. c. The OCT B-scan shows parafoveal RPE and outer retinal atrophy with hypertransmission into the choroid and sclera (red and purple arrows). This is the so-called “flying saucer” sign. The nasal atrophy (purple arrow) is more advanced than the temporal atrophy (red arrow). There is also an incidental epiretinal membrane.