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  • Parts A–B, D–F courtesy of Tero Kivelä, MD.
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    Ocular Pathology/Oncology

    Imaging of choroidal tumors. Choroidal melanoma with orange pigment (A) that exhibits increased autofluorescence with fundus autofluorescence imaging (B). Note also increased autofluorescence associated with recent leakage (subretinal fluid) inferior to the tumor. The tumor’s center shows decreased autofluorescence due to RPE loss. The A‑scan ultrasonogram shows characteristic low internal reflectivity (arrow) of a choroidal melanoma (C). B‑scan ultrasonography is used primarily to show the tumor location and its topography. Typical features include low internal reflectivity, leading to apparent choroidal excavation relative to the surrounding more reflective healthy choroid (D), and a mushroom or collar-button shape of larger tumors (E). Posterior extrascleral extension of tumor (between arrows) is apparent as a low-reflective orbital lesion in contact with the sclera (F).