Corneal laser in vivo confocal microscopy images of patients with neuropathic corneal pain. Images pretreatment (A and C) demonstrate presence of microneuromas (black arrows), decreased nerve density, and increased tortuosity. Following 4 and 6 months of treatment with autologous serum tears 8 times per day and low-dose anti-inflammatory therapy, sub-basal corneal nerve density is increased, and microneuromas are not present (B and D). Size bar = 100 μm.