• Courtesy of Alison Skalet, MD, PhD.
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    Ocular Pathology/Oncology

    Malignant transformation of choroidal nevus to melanoma. A, Small choroidal nevus. B, After an observation period of 13 months, the nevus has expanded its borders and acquired surface lipofuscin. C, A different patient with a small peripapillary choroidal nevus. D, The nevus shown in part C demonstrated substantial growth and emergence of surface lipofuscin after an observation period of 6.5 years.