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  • Part A courtesy of Harry H. Brown, MD; part B courtesy of Robert H. Rosa, Jr, MD.
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    Ocular Pathology/Oncology

    Necrotizing granulomatous scleritis. A, An area of necrobiotic sclera (asterisk) is sequestered by a zonal inflammatory reaction of histiocytes, lymphocytes, and plasma cells. B, High-magnification photomicrograph of scleral (S) biopsy illustrates palisading arrangement of histiocytes and multinucleated giant cells (arrows) around necrobiotic scleral collagen (asterisk).