Pigment dispersion syndrome. A, Gross photograph demonstrating radially oriented transillumination defects in the iris. B, Melanin is present on the anterior surface of the lens. C, Note the focal loss of iris pigment epithelium (arrow). Chafing of the zonular fibers against the epithelium may release the pigment that is dispersed in this condition. D, Note the accumulation of pigment in the trabecular meshwork.