(A) Fundus photograph of left eye of 65-year-old man with moderate cataract in setting of mild NPDR without CSME. Visual acuity of 20/70 was consistent with density of cataract. (B) About 8 weeks after ECCE, visual acuity had deteriorated to 20/200 and CSME was present. (C,D) Intravenous fluorescein angiography performed 8 weeks after cataract surgery reveals relatively few microaneurysms in phase (C) and diffuse leakage of fluorescein materials in recirculation phase. (D) Vision remained poor in the eye due to chronic macular edema despite medical and laser treatment.