• Illustration by Cyndie C.H. Wooley.
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    Physiologic functions of the RPE. Additional functions (not shown) include its role in synthesis and remodeling of the interphotoreceptor matrix, formation of the outer blood–retina barrier, and formation of the basal lamina of Bruch membrane. PEDF = pigment epithelium–derived factor; VEGF = vascular endothelial growth factor.