Histopathologic Findings in Dead Bag Syndrome

In this interview from AAO 2021, Dr. Liliana Werner discusses the histopathologic findings of "dead bag syndrome," a condition characterized by a late postoperative IOL dislocation with a clean, clear capsular bag and no noticeable fibrotic changes.

In Dr. Werner's study, capsular bags from suspected cases were removed due to in-the-bag dislocation of the posterior chamber IOL. Histopathologic examination showed capsular thinning or splitting. Lens epithelial cells were completely absent on one specimen, and the other specimens had only sparse epithelial cells on the inner surface of the anterior capsule. Weakness of zonular attachments appears to be an associated finding. Further studies are needed to understand the etiology of dead bag syndrome.

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