In this presentation from Pediatric Ophthalmology Subspecialty Day 2022, Dr. Donny Suh reviews a large-scale study that evaluated the effectiveness of overminus spectacle therapy in children with intermittent exotropia. The randomized trial was conducted to assess the on-treatment and off-treatment effects of overminus lenses on distance intermittent exotropia control, as well as the effect of overminus correction on myopia progression. Among other findings, myopic shift from baseline to 12 months was greater in the overminus than the nonoverminus group, with 33 of 189 children (17%) in the overminus group versus 2 of 169 (1%) in the nonoverminus group experiencing a shift of more than 1 D.