MAR 18, 2009
Comprehensive Ophthalmology, Retina/Vitreous
The Endophthalmitis Vitrectomy Study (EVS) has strongly influenced the management of acute postoperative endophthalmitis since the release of its findings in 1995.1 The EVS confirmed the visual benefit of pars plana vitrectomy in patients presenting with visual acuity of light perception only in which acute postoperative endophthalmitis occurs within six weeks of cataract extraction or secondary IOL implantation. The study also showed that when intravitreal antibiotics are given, systemic antibiotics-in this case intravenous ceftazidime and amikacin-provide no added visual benefit. However, a re-evaluation of the EVS recommendations seems appropriate, since treatment modalities have changed since the EVS results were released.