Proliferative vitreoretinopathy (PVR) is a complication of retinal detachment (RD), causing failure of successful RD repair in approximately 10% of cases. Once PVR is present, subsequent successful repair is achieved in approximately 50% to 75% of cases. Even after successful retinal reattachment, anterior PVR can proliferate over the ciliary body, leading to ciliary body deformation, hypotony and the development of phthisis bulbi. Efforts to remove anterior PVR to address hypotony and prevent phthisis are limited by visualization of the scar tissue in the anterior periphery behind the iris and by anterior segment abnormalities that are not uncommon in these cases. This video features a case of recurrent RD, anterior PVR, hypotony and severe corneal opacity that prevented a traditional top-down viewing technique. The evolution of endoscopy-guided 23-25 gauge vitrectomy technologies allowed us to perform a safe and efficient surgery, removing all anterior and posterior retina tractions and macular membrane and exploring the ciliary body site, all retina breaks and the subretinal space without needing a corneal surgery or keratoprosthesis.