Geographic atrophy

Geographic atrophy (GA). A, Color fundus photograph of right eye, demonstrating advanced GA. B, Corresponding fundus autofluorescence image from the same patient. The areas of RPE atrophy are hypoautofluorescent (dark gray or black), the areas of “sick” RPE are hyperautofluorescent (brighter than background), and the areas of healthy RPE are gray. C, Corresponding near-infrared reflectance image in the same patient (left). Large choroidal vessels are visible through the central area of GA. Green arrow marks the location seen in the SD-OCT image (right) showing complete atrophy of photoreceptors, RPE, and choriocapillaris.