Myopic Foveoschisis After Vitrectomy
By Jean Shaw
Selected by Andrew P. Schachat, MD
Journal Highlights
Ophthalmology Retina, December 2022
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Beaumont et al. set out to assess time to resolution of myopic foveoschisis (MFS) following pars plana vitrectomy (PPV). They found that most of these cases completely resolve by the end of the first postsurgical year, and they suggested that a decrease in central foveal thickness (CFT) and early resolution of inner retinoschisis (IRS) could be used as early biomarkers of surgical success.
For this retrospective observational case series, the researchers identified patients with a diagnosis of MFS in their database (N = 131). Those who underwent surgery and were followed for at least six months were included in the analysis (n = 36; 39 eyes). The researchers measured time to resolution of four morphological criteria: CFT, IRS when present, foveal outer retinoschisis (ORS), extrafoveal ORS, and foveal detachment (FD) when present.
Anatomical success occurred in 82% of cases at the end of follow-up (mean, 14.8 ± 12.9 months) and in more than 80% cases during the first year. At the 12-month mark, CFT had decreased by at least 50 μm in 97% of eyes.
IRS occurred in 18 eyes and had fully resolved in all 18 at a median time of one month (range, 1-6 months). Foveal ORS occurred in all eyes and resolved in 82% at a median of three months (range, 1-16 months). FD occurred in 23 eyes and resolved in 91% at a median of six months (range, 1-24 months). Extrafoveal ORS occurred in all eyes and resolved in 59% at a median of 12 months (range, 1-24 months).
In their discussion, the authors noted that IRS and CFT appear to be good indicators of final surgical success—and that the slower resolution of the ORS and FD suggests the involvement of both traction and cellular dysfunction.
The original article can be found here.