2020–2021 BCSC Basic and Clinical Science Course™
5 Neuro-Ophthalmology
Chapter 10: The Patient With Pupillary Abnormalities
Disorders of Pupillary Reactivity: Light–Near Dissociation
Aberrant Regeneration
Light–near dissociation can also result from aberrant regeneration of damaged nerves that restores the near reflex but not the light reflex. Misdirected growth can occur after traumatic injury or chronic compression of CN III. Sometimes aberrant regeneration involves the medial rectus fibers and pupillary contraction occurs during attempted adduction. This synkinetic pupil movement can resemble light–near dissociation.
Excerpted from BCSC 2020-2021 series: Section 5 - Neuro-Ophthalmology. For more information and to purchase the entire series, please visit https://www.aao.org/bcsc.