By Hosam Ibrahim El Sheha, MD
    Cornea/External Disease

    A 56 year old female patient with ocular cicatricial pemphigoid exhibiting total limbal stem cell deficiency associated with vascularized corneal scarring and symblepharon was treated with superficial keratotomy, fornix and ocular surface reconstruction with amniotic membrane transplantation and direct transplantation of oral mucosal graft to the limbal region. We achieved a stable ocular surface, deep fornix and clear cornea with improvement of visual acuity. This approach appears to offer an alternative to allogeneic grafts such as keratolimbal allograft and avoids the potential adverse effect of systemic combined immunosuppression.