• Comprehensive Ophthalmology

    The authors of this study evaluated the reliability of lens density measurement with anterior segment optical coherence tomography (OCT) in 55 eyes of 55 patients with age-related cataracts. Based upon their results, the investigators concluded that anterior segment OCT nucleus density measurement is reliable and correlates with Lens Opacity Classification System Version III (LOCS III) scores.

    One eye from each subject was selected randomly for lens evaluation. After dilation, lens photographs were taken with a slit lamp and graded against the LOCS III standardized condition. Anterior segment OCT imaging (using Visante OCT Model 1000, Carl Zeiss Meditec) was performed on the same eyes with a high-resolution scan.

    The authors found significant correlations between anterior segment OCT nuclear density measurements and LOCS III nuclear opalescence and nuclear color scores. The results were found to have high repeatability, with a low coefficient of variation and high intraclass correlation coefficient. The authors noted that the learning curve for performing lens imaging with anterior segment OCT is much shorter than for LOCS III grading.