Neuro-ophthalmology and anti-GQ1b antibody syndromes

This paper reviews the clinical neuro-ophthalmologic aspects of Miller Fisher syndrome (MFS), atypical MFS, Guillain-Barré syndrome with ophthalmoplegia and Bickerstaff's brainstem encephalitis, and highlights the laboratory and imaging abnormalities and treatment of these disorders. The author also discusses differing opinions on the origins of these syndromes and some of the biology of the anti-GQ1b antibody, which has been linked to these syndromes. It is important for ophthalmologists to be familiar with these syndromes because of the ocular motility deficits that may accompany their manifestation.

Financial Disclosures
Dr. Vaphiades has no financial interests to disclose.