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    Plaque Brachytherapy: Radiating Positivity

    AAO 2022 Video Program
    Ocular Pathology/Oncology

    This video reviews the concept of plaque brachytherapy, the various types of plaques available, different radiation sources, treatment planning dosimetry and calculations, target disease spectrum, surgical placement, and postradiation outcomes in terms of local tumor control and prognosis. Plaque brachytherapy is an evolving yet effective globe- and vision-sparing modality for the treatment of intraocular tumors by transscleral irradiation of the tumor base with a radioactive implant. The American Brachytherapy Society (ABS), in collaboration with the international, multicenter Ophthalmic Oncology Task Force (OOTF), was assembled to reach a consensus on establishing practice guidelines and setting standards of care for intraocular tumors. This technique provides the advantage of focal radiation, eliminating damage to the adjacent structures, minimizing periorbital tissue damage, and avoiding cosmetic disfigurement owing to a lack of retarded bone growth as seen in external-beam radiotherapy. Thus, it reduces the risk of metastasis, and with recent advances, it provides a shorter duration of treatment.

    Financial Disclosure: Drs. Rolika Bansal, Santosh Honavar, and Shiva Shankar Talloju disclose no financial relationships.