2020–2021 BCSC Basic and Clinical Science Course™
4 Ophthalmic Pathology and Intraocular Tumors
Part I: Ophthalmic Pathology
Chapter 5: Conjunctiva
Inflammation
Pyogenic Granuloma
Pyogenic granuloma (exuberant granulation tissue) appears as a fleshy, red, pedunculated, nodular elevation on the conjunctival surface, typically occurring in association with a chalazion (on the palpebral conjunctiva) or a punctum or at a site of prior accidental or surgical trauma. Granulation tissue is a reparative process that is necessary for wound healing after inflammation or injury. The term “pyogenic granuloma” is a misnomer because the lesion is not pus producing and is not granulomatous. Rather, pyogenic granuloma is an exuberant proliferation (overgrowth) of granulation tissue composed of acute and chronic inflammatory cells and radially arranged, proliferating capillaries within a loose connective tissue framework (Fig 5-10).
Excerpted from BCSC 2020-2021 series: Section 4 - Ophthalmic Pathology and Intraocular Tumors. For more information and to purchase the entire series, please visit https://www.aao.org/bcsc.