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  • Courtesy of André Salgado Araújo Marques, Ana Catarina Almeida.
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    Pediatric Ophth/Strabismus

    Megalocornea is a rare non-progressive corneal disorder in which the corneal diameter largely exceeds the normal values for the newborn or toddler (equal or greater than 13mm). It is usually bilateral, and in most cases is X-linked, so the majority of the patients are male. Although a similar picture may be seen in severe congenital glaucoma with buphthalmus, in megalocornea the IOP is normal, there is no corneal edema or opacification, nor is there Haab striae. Keratoglobus may also resemble megalocornea, but the corneal thickness is more or less evenly decreased in the periphery, which was not the case. Although children may have myopia or astigmatism, they usually develop and retain good vision if regular follow-up and careful refraction are provided. In this case, it was an isolated finding in an otherwise healthy toddler, but it may be associated with conditions such as Alport syndrome, Marfan syndrome, Ehlers-Danlos syndrome, Down syndrome and others