• IRIS Registry Data Analysis

  • Hoskins Center IRIS Registry Research Fund

    As an ophthalmologist you are a scientist – you’re inquisitive and observant and enjoy testing your hypotheses.

    Throughout your career you’ve had hunches and noticed suggestive patterns but didn’t have a practical way of following up on your perceptions.

    What if you had the opportunity to pursue your idea with funding and a supportive team of data scientists who have access to millions of patient data points?

    What question would you ask?

    The H. Dunbar Hoskins Jr., MD, Center for Quality Eye Care IRIS® Registry Research Fund supports Academy members in private practice who want to use the Academy IRIS Registry (Intelligent Research in Sight) database to answer important clinical questions.

    The goal of the fund is to give Academy members the opportunity to harness big data.

    2019 Winners of The H. Dunbar Hoskins Jr., MD, Center for Quality Eye Care IRIS® Registry Research Fund are:

    • Rahul Khurana, M.D., Northern California Retina Associates. New treatment options for age-related macular degeneration and diabetic retinopathy have saved millions of Americans from blindness. But millions more are at risk of losing their vision to these two devastating conditions because they don’t return to their ophthalmologists for follow-up treatment. Dr. Khurana will use IRIS Registry data to identify risk factors that contribute to patients’ failure to return to their ophthalmologist for follow-up care.
    • Wilkin Parke III, M.D., VitreoRetinal Surgery, PA. There are three surgical options for treating the most common type of retinal detachment, rhegmatogenous retinal detachment. But only one, pneumatic retinopexy, is performed in the ophthalmologist’s office. It has several advantages: it’s more comfortable for the patient, recovery is quicker, and it’s less expensive. While clinical trials show this technique is effective, physicians have been slow to adopt it. Dr. Parke will use IRIS Registry data to describe the real-world outcomes of pneumatic retinopexy and to identify which patients are best suited for this type of surgery.
    • Sudeep Pramanik, M.D., Mid Atlantic Cornea Consultants, clinical associate professor of Ophthalmology, University of Maryland. In the last decade, endothelial keratoplasty has become the most common type of corneal transplant surgery performed in the US. But the last, large database study evaluating this type of surgery is outdated, having looked at data from 2001 to 2009. Dr. Pramanik will use IRIS Registry data to evaluate the real-world indications and outcomes of this common procedure, which could potentially lead to even better results for patients.
    • Raj Maturi, M.D., Midwest Eye Institute, associate professor of Ophthalmology, Indiana University School of Medicine. Treatment options for patients with diabetic macular edema have expanded recently. Many patients get more than one type of treatment to get the best results. Dr. Maturi will use IRIS Registry data to determine if physicians throughout the country are using all the treatment options available to improve outcomes for their patients. Additionally, Dr. Maturi will investigate whether patients who don’t smoke respond better to treatment compared with patients who do smoke.

    Four abstracts for the 2020 Academy Annual Meeting were submitted, based on efforts on these projects.

    How it Works

    The Hoskins Center IRIS Registry Research Fund will fund four or more IRIS Registry analytics projects in 2020, with more opportunities expected in the future.

    Each award is $35,000.

    • $5,000 goes to the investigating member.
    • $30,000 goes to the Academy for expenses related to data access and analysis.

    Awardees will also be supported for travel to the Academy office in San Francisco. During this visit, awardees will learn about the IRIS Registry database, receive an introduction to big data analytics and work closely with Academy staff on the analysis.

    Eligibility Requirements

    To be eligible for the grant, you must be:

    • A member of the Academy
    • In private practice
    • A participant in the IRIS Registry or working towards participation

    Application Process 

    Application Overview

    • What is the question or hypothesis you would like to investigate?
    • How do you think big data will help answer your question?
    • What is the clinical significance of your idea?
    • Why are you interested in big data?
    • Do you have experience with big data and/or research?
    • Do you have a specific timeline for analysis?
    • What is your availability for participating in analysis?
    • How does your idea support the Academy’s mission to protect sight and empower lives?
    • Do you know which IRIS Registry data elements you would like to use? (A list of options is available.)
    • Upload your CV or NIH-style biosketch

    How to Apply

    Evaluation Criteria

    • Significance: Does the proposal address an important problem or critical barrier to progress in the field?
    • Candidate: Does the member have high interest and adequate time to devote to the project?
    • Innovation: Is this a unique question for the IRIS Registry?
    • Approach: Is the proposal well thought out? Is the project feasible?


    • The IRIS Registry Analytics Committee will review applications and notify the selected award recipients during summer 2020.