Transplantation of human amniotic membrane (hAM) has been gaining popularity for the repair of recurrent macular holes or posterior pole breaks where other measures fail, such as in eyes with pathological myopia. In this case of pathological myopia, the patient had schizophrenia and lost light perception in the fellow eye after multiple operations. The patient presented with retinal detachment associated with a large macular hole and four large retinal breaks at the posterior pole. The axial length was 35 mm. A pars plana vitrectomy combined with phacoemulsification was applied, and two hAM grafts were placed over the hole and breaks and tamponaded with silicone oil. Two years after silicone oil removal, the retina remained attached and the vision at the level of hand movements could be preserved.

This video was noted as being one of the Best of AAO 2023.