Optical coherence tomography angiography (OCTA) is a relatively new modality allowing detailed imaging of the retinal vasculature. It is a rapid, low-cost, noninvasive procedure that, importantly, allows for visualization of the superficial and deep capillary plexuses separately. In this video, the presenters showcase OCTA images of the superficial and deep retinal plexuses and demonstrate a novel technique to evaluate the size and characteristics of the foveal avascular zone (FAZ) therein. The group performed OCTA scans on 117 healthy participants and examined the effect of ocular and demographic factors on FAZ size via univariate and multivariate regression analyses. The factors examined included central retinal thickness, axial length, spherical equivalent, and choroidal thickness. Superficial and deep FAZ areas correlated significantly with gender, central retinal thickness, and spherical equivalent. In high myopes, FAZ size was significantly smaller in both superficial and deep layers, demonstrating the potential of FAZ size as a proxy measurement for other ocular factors.

Financial Disclosures: Dr. Colin Tan discloses a financial relationship with Bayer Healthcare Pharmaceuticals (Lecture Fees/Speakers Bureau). Drs. Kevin Li and Wei Jie Isaac Chay disclose no financial relationships.