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Lateral canthus basal cell carcinoma (BCC)
NOV 02, 2023
Excision of lateral canthus BCC and reconstruction of posterior lamella using periosteal flap and anterior lamella using Tripier myocutaneous flap.
Image
0
151
Recurrent iris metastasis of primary small cell lung carcinoma
SEP 26, 2023
A case of small cell lung carcinoma with iris metastasis was treated with external beam radiotherapy with initial resolution of the lesions. The metastases then recurred, as depicted and the patient died from metastatic disease shortly thereafter.
Image
0
52
Conjunctival nevus
SEP 18, 2023
Conjunctival nevus.
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0
23
Ciliary body cyst
MAR 27, 2023
A 35-year-old man complains of shadows in temporal side of his right eye for the last 4 months. A ultrasound biomicroscopy confirms the cystic nature of the mass.
Image
0
134
Iris racemose hemangioma
JAN 23, 2023
Fluorescein angiography of a 66 year-old patient presenting with an iris racemose hemangioma.
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123
Primary acquired melanosis
JAN 16, 2023
Primary acquired melanosis (PAM)/conjunctival melanocytic intraepithelial neoplasia (C‑MIN). A, Mild PAM, involving 1 clock-hour of conjunctiva; unlikely to harbor atypia and may be observed. B, Histology of PAM (C-MIN) without atypia. H&E stain (top) shows melanocytic proli…
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0
335
Cysticercosis
JAN 03, 2023
Multipart image showing multiple cysticercosis in brain, orbital muscles, orbital fat, optic nerve sheath.
Image
0
197
Pigmented ocular surface squamous neoplasia
SEP 23, 2022
Pigmented OSSN show hyperplastic and hyperchromatic cells, dyskeratosis, keratin pearls, loss of cellular cohesion, and atypical mitotic figures. In pigmented OSSN, the pigmentation owing to abnormal proliferation of melanocytes in the lesions are noted.
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0
36
Ocular surface squamous neoplasia (OSSN)
JUN 23, 2022
A 52-year-old male patient presented with a painless rapidly growing grayish lesion in his left eye that he felt was interfering with his vision in dim light over the last month. Slit-lamp examination showed a grayish-white semitransparent slightly elevated lesion extending…
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39
Retinoblastoma ancillary imaging
MAR 24, 2022
B-scan ultrasonographic findings demonstrate a dome-shaped retinal lesion with characteristic scattered calcifications within the tumor
(arrows)
.
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0
18
Retinoblastoma
MAR 24, 2022
Retinoblastoma.
A,
Clinical photograph shows leukocoria and strabismus associated with an advanced intraocular tumor.
B,
Higher-magnification view through the pupil. Note the large retrolental tumor and secondary total exudative retinal detachment.
Image
0
2
Leukemic infiltration of the optic nerve
MAR 24, 2022
Leukemic infiltration of the optic nerve, an ophthalmic emergency.
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0
9
Trilateral retinoblastoma
MAR 24, 2022
Contrast-enhanced sagittal T1-weighted magnetic resonance image of the brain demonstrates a large midline cerebral lesion (asterisk) involving the pineal region in a child with bilateral retinoblastoma; this is consistent with a pinealoblastoma (primitive neuroectodermal tum…
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0
16
Retinal capillary hemangioblastoma
MAR 24, 2022
Retinal capillary hemangioblastoma (RCH), clinical photographs. Dilated, tortuous retinal feeder artery and draining vein emanate from the optic nerve head (A), leading to the red to orange peripheral retinal tumor (B). An optic nerve head hemangioblastoma causes traction in…
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0
36
Vasoproliferative tumors
MAR 24, 2022
Vasoproliferative tumor (VPT). A, Color fundus photograph shows a VPT in the temporal periphery of the right eye (arrow). The tumor appears as a pink and yellow elevated mass with tortuous internal vasculature and associated subretinal fibrosis and exudate (asterisks).B, B-s…
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0
491
Vitreous seeds
MAR 24, 2022
A, Clinical photograph shows a large, spherical vitreous seed (arrow) in retinoblastoma. B, OCT findings in a child with advanced retinoblastoma demonstrated an intact fovea, a dusting of small hyperreflective seeds on the retinal surface, and a hollow reflective cystic stru…
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26
Post trachomatous degenerations
FEB 24, 2022
A 54-year-old male presented with persistent foreign body sensation that was partially relieved with artificial tears eye drops in his right eye. On everting the upper eye lid, confluent concretions of the tarsal conjunctival surface was observed with multiple ones eroding t…
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466
Caruncle keratoacanthoma
JUL 20, 2021
Caruncle keratoacanthoma is a rapidly growing epithelial proliferation.
Image
0
23
Ocular surface squamous neoplasia (OSSN)
JUL 20, 2021
Ocular surface squamous neoplasia (OSSN) involves abnormal growth of dysplastic squamous epithelial cells on the surface of the eye.
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0
327
Conjunctival pyogenic granuloma
JUL 20, 2021
Conjunctival pyogenic granuloma is a common benign vascular proliferation, appearing as smooth, red-purple, sessile or pedunculated lesions.
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494
Von Hippel Lindau disease
JUN 16, 2021
Fundus Montage of a 34-year-old female with diagnosis of von Hippel Lindau disease and presenting 2 cappilary hemangiblastomas.
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1
Endophthalmitis
JUN 02, 2021
(A) Straphylococcus epidermidis endophthalmitis in a 86-year-old diabetic man 1 week after small-incision phacoemulsification with posterior chamber intraocular lens implantation. Visual acuity in hand motions at 1 ft. (B) About 5 months later and after pars plana vitrectomy…
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0
1
Choroidal melanoma
MAY 25, 2021
Choroidal melanoma, clinical appearance. A, B, Choroidal melanomas may be quite thin. Note the prominent surface lipofuscin in each case and the large area of flat involvement surrounding the elevated portion centrally in part B (arrowheads); however, they are more commonly…
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0
9
Multimodal imaging of choroidal nevi
MAY 25, 2021
Multimodal imaging of choroidal nevi. A, B, Color fundus photographs document the tumor borders and surface appearance of 2 thin choroidal nevi. C, Fundus autofluorescence (FAF) reveals minimal RPE disturbance in the area of the choroidal lesion. D, FAF shows decreased autof…
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40
Choroidal nevi
MAY 25, 2021
Choroidal nevi, clinical appearance. Choroidal nevi are generally thinner than 2 mm and variably brown. They may be solitary (A) or multiple (B). Nevi may demonstrate drusen on their surface (A, arrow). C, Small nevi lack retinal pigment epithelial (RPE) changes. D, Large ne…
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0
4
Malignant transformation of choroidal nevus to melanoma
MAY 25, 2021
Malignant transformation of choroidal nevus to melanoma. A, Small choroidal nevus. B, After an observation period of 13 months, the nevus has expanded its borders and acquired surface lipofuscin. C, A different patient with a small peripapillary choroidal nevus. D, The nevu…
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1
Iris melanoma
MAY 25, 2021
Iris melanoma, clinical appearance. A, The lesion can be amelanotic with visible intrinsic vascularity. B, Alternatively, it may be densely pigmented, obscuring any blood vessels (note the dispersed pigment on the iris stroma). C–H, The slit-lamp (C, D), gonioscopic (E, F),…
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40
Differential diagnosis, iris melanoma
MAY 25, 2021
Differential diagnosis of iris melanoma. A, A pigment epithelial cyst (asterisk) can bow the iris forward focally. The cyst is visible after dilation. B, Multiple Lisch nodules in neurofibromatosis. Lisch nodules are melanocytic hamartomas that are typically tan to golden br…
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76
Multimodal imaging of choroidal melanomas
MAY 25, 2021
Multimodal imaging of choroidal melanomas. A, B, Wide-angle color fundus photographs document the tumor borders and surface appearance of 2 choroidal melanomas. C, FAF image of the lesion shown in part A reveals increased diffuse autofluorescence associated with subretinal f…
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0
45
Diagnostic evaluation, transillumiantion and B-scan
MAY 25, 2021
Intraoperative localization of melanoma for treatment purposes. A, Transillumination of the eye reveals a shadow at the site of a choroidal melanoma. This technique may be used to mark the tumor base to ensure accurate placement of a radioactive plaque. B, B-scan ultrasonogr…
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0
10
Congenital hypertrophy of the RPE (CHRPE)
MAY 25, 2021
Congenital hypertrophy of the RPE (CHRPE), various clinical appearances. A, Large, homogeneously black CHRPE lesion. B, CHRPE with atrophic lacunae. C, Grouped pigmentation of the RPE represents a variant of CHRPE. D, Appearance of the RPE hamartoma associated with familial…
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0
248
Benign iris melanocytic lesions
MAY 25, 2021
Benign iris melanocytic lesions, clinical appearance. A, Iris freckles are flat and often multiple. B–D, Iris nevi have a variable appearance and may be flat (B, C) or nodular (D). They may cause ectropion uveae (B). C–H, The slit-lamp (C, D), gonioscopic (E, F), and ultraso…
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6
Optic nerve sheath meningioma
MAY 24, 2021
Optic nerve sheath meningioma. A, Gross photograph showing a globe (white bracket) with massive thickening (red bracket) of the optic nerve and sheath just posterior to the sclera, secondary to meningioma. B, This meningioma (asterisks; different from that shown in part A) h…
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0
40
Optic nerve coloboma and pit
MAY 24, 2021
Optic nerve coloboma and pit. A, Fundus photograph of the right eye shows a colobomatous defect in the inferonasal optic nerve (arrow). B, Photomicrograph shows gliotic, disorganized retina (asterisk) that prolapses into the optic nerve head defect, which is lined by excavat…
Image
0
2
Low-grade B-cell lymphoma
MAY 18, 2021
Low-grade B-cell lymphoma of the orbit. A, Low-magnification photomicrograph shows sheets of small, dense, uniform lymphocytes forming vague follicular arrangements (arrows). B, Higher magnification shows a lymphoid follicle with a germinal center (asterisk. C, Dutcher bodie…
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0
3
Solitary fibrous tumor
MAY 18, 2021
Solitary fibrous tumor (hemangiopericytoma-like). A, Photomicrograph demonstrates a cellular tumor with a characteristic slitlike and branching vascular (staghorn) pattern. B, Photomicrograph demonstrates closely packed cells with oval to spindle-shaped vesicular nuclei.
Image
0
2
Fibrous histiocytoma
MAY 18, 2021
Fibrous histiocytoma. Photomicrograph illustrates the storiform (whorled and matlike) growth pattern.
Image
0
10
Fibrous dysplasia
MAY 18, 2021
Fibrous dysplasia. The bony trabeculae are often C-shaped, composed of immature woven bone, and surrounded by a fibrous stroma.
Image
0
3
Reactive lymphoid hyperplasia
MAY 18, 2021
Reactive lymphoid hyperplasia of the orbit. The photomicrograph shows a dense infiltrate of lymphoid cells with a follicular pattern and well-formed germinal centers (asterisks). A panel of immunohistochemical stains (not shown) demonstrated a polyclonal population of lympho…
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0
81
Immunoglobulin G4–related disease
MAY 18, 2021
Immunoglobulin G4–related disease (IgG4-RD). A, CT image from a 67-year-old woman who presented with a 3-year history of an enlarging painless mass of the right lacrimal gland fossa, which was identified on CT as a homogeneously enhancing, circumscribed mass diffusely involv…
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0
4
Adenoid cystic carcinoma
MAY 18, 2021
Adenoid cystic carcinoma of the lacrimal gland. A, Low-magnification photomicrograph shows numerous invasive tumor lobules. B, Note the characteristic cribriform (“Swiss cheese”) pattern of growth. C, The solid lobules of tumor represent the basaloid pattern, which is associ…
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0
1
Neurilemoma
MAY 18, 2021
Neurilemoma (schwannoma). A, The Antoni A pattern. Spindle cell nuclei are arranged in linear palisades. B, Palisading of nuclei may form a Verocay body (asterisks). C, The Antoni B pattern consists of a loosely arranged, mucoid stroma and represents degeneration within the…
Image
0
8
Orbital cavernous hemangioma
MAY 18, 2021
Orbital cavernous hemangioma. A, CT scan (axial view) shows a well-circumscribed retrobulbar intraconal mass (asterisk). B, Low-magnification photomicrograph demonstrates large blood-filled spaces that are separated by relatively thin septa. C, Higher-magnification photomicr…
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0
49
Sarcoidosis
MAY 17, 2021
Sarcoidosis. A, Chorioretinitis in the fundus. B, Optical coherence tomography of the unaffected eye (top) and the eye with chorioretinitis (bottom) demonstrating thickening of the choroid in the eye with inflammation. C, Biopsy of a sarcoid nodule showing epithelioid his…
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0
7
Apocrine hidrocystoma
MAY 17, 2021
Apocrine hidrocystoma. A, Low-power photomicrograph shows a partially collapsed cyst that is lined by a double layer of epithelium (ie, an inner, low cuboidal layer and an outer, flattened myoepithelial layer). The lumen appears empty as the clear liquid contents are not vis…
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0
11
Choroidal osteoma
MAY 17, 2021
Choroidal osteoma. This choristomatous lesion is composed of compact bone (
asterisk
) and intratrabecular connective tissue.
Image
0
2
Merkel cell carcinoma
MAY 17, 2021
Merkel cell carcinoma (MCC). A, High-magnification photomicrograph shows that the tumor is composed of blue cells with round, granular-appearing nuclei and frequent mitoses. B, Immunohistochemistry with cytokeratin 20 shows the characteristic pattern of perinuclear dotlike s…
Image
0
2
Irritated seborrheic keratosis
MAY 17, 2021
Irritated seborrheic keratosis (also known as inverted follicular keratosis). A, Low-magnification photomicrograph shows a papillary epidermal proliferation with hyperkeratosis on the surface. Clinically, this lesion appeared as a cutaneous horn. B, High-magnification photom…
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0
766
Choroidal hemangioma
MAY 17, 2021
Choroidal hemangioma with a large number of thin-walled, variably sized vessels within the choroid. A, Low-magnification view shows exudative retinal detachment overlying the lesion (asterisk). Arrows designate Bruch membrane. B, Higher-magnification photomicrograph from a d…
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0
13
Aniridia
MAY 17, 2021
Aniridia, with a rudimentary iris present (visible near the limbus in this photograph). Cataract is also present.
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0
1
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