Update on the structure-function relationship in glaucoma

This article outlines the current evidence and mathematical models linking structure and function in glaucoma.

Large clinical trials have demonstrated that both structural and functional change are apparent in advanced stages of disease, and that detectable structural abnormality may precede functional abnormality in some patients, whereas the converse is true in other patients.

The article's authors conclude that the future will bring an integration of structural and functional test results to improve glaucoma monitoring and diagnosis.