Adult-onset asthma with periocular xanthogranuloma (AAPOX) disease. A, Clinical photography showing yellow subcutaneous lesions on the upper and lower eyelids. B, Intraoperative image shows thick yellowish unencapsulated xanthogranulomatous lesions infiltrating the eyelid tissues. C, H&E stain of the lesion shows numerous foamy histiocytes and mature lymphoid follicles (arrows).