Pleomorphic adenoma (benign mixed tumor) of the lacrimal gland. A, Clinical appearance. A superotemporal orbital mass is present, causing proptosis and downward displacement of the left globe. B, CT scan (coronal view) demonstrating left orbit tumor. C, Low-magnification photomicrograph shows the circumscribed nature of this pleomorphic adenoma. D, Note both the neoplastic epithelial elements (arrow) and the fibromyxoid stroma (asterisk). E, Well-differentiated glandular structures with lumina (asterisk). The outer myoepithelial layer can become metaplastic to form other mesenchymal tissue (eg, adipose, cartilage [arrow]).