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  • Part A courtesy of Robert H. Rosa Jr, MD; part B courtesy of Steffen Heegaard, MD.
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    Ocular Pathology/Oncology

    Sub-RPE infiltrates in a patient with primary intraocular lymphoma (PIOL). A, Note the characteristic speckled pigmentation over the tumor detachments of the RPE. B, OCT image shows disruption of the RPE cell layer and tumor cells on top of the RPE cells (arrows).