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  • Parts A, B courtesy of Steven A. Newman, MD; part C courtesy of Michael S. Lee, MD; part D courtesy of Anthony C. Arnold, MD.
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    A, Disc photograph in retrobulbar optic neuritis, showing normal appearance. B, A central scotoma is shown on automated perimetry results. C, T1-weighted axial MRI scan of the orbits with fat-suppression and gadolinium administration, showing enhancement of the right intraorbital optic nerve (arrow). D, T2-weighted axial MRI scan of the brain, demonstrating multiple white matter hyperintensities (arrows) consistent with demyelination.