An alkali burn, shown here, can be more devastating to the eye because the alkaline agent dissolves the corneal tissue and continues to cause damage long after the initial chemical contact. The treating physician needs to ensure all particles of an alkaline agent are removed, or they will continue to release alkali. Following thorough irrigation, refer to an ophthalmologist emergently. Corneal melting or perforation can result from prolonged epithelial defects, and the risk of perforation persists until the epithelium is intact. Glaucoma, cataract, and chronic surface disease can occur as a later complication.