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    Retina/Vitreous

    Microaneurysms are usually the earliest visible manifestation of diabetic retinopathy. They appear as tiny red dots scattered in the retina posteriorly (single arrows). They may be surrounded by a ring of yellow lipid, or hard, exudates (double arrow). Exudates are the result of vascular leakage, but the specific leaking microaneurysm may not be visible ophthalmoscopically.