Tears in the retinal pigment epithelium (RPE). A, Fundus photograph of a patient with choroidal neovascularization (CNV) who was given an intravitreal injection of an anti–vascular endothelial growth factor agent and developed what appeared to be 4 RPE tears (arrows). B, Fundus AF reveals the absence of autofluorescence and an increased signal where the RPE appears to be scrolled, thus confirming the CNRPE tear (arrows). Small areas of atrophy are also revealed by the autofluorescence (arrowheads).