Dr. Fairooz Manjandavida discusses the various presentations of ocular-surface squamous neoplasia (OSSN), a blanket term currently used for precancerous and cancerous conjunctival and corneal epithelial lesions. It is a spectrum that includes conjunctival dysplasia, intraepithelial neoplasia, and malignant squamous cell carcinoma (SCC). Based on her experience, Dr. Manjandavida finds that the presence of keratin, feeder vessels, and positive Rose bengal staining have a high sensitivity and specificity for diagnosing OSSN (unpublished data). Primary, wide, surgical excision remains the gold standard to treat OSSN, and proper surgical protocols can reduce the rates of recurrence.