Bevacizumab appears safe for treating PDR after photocoagulation therapy

This prospective study included 24 patients (33 eyes) with proliferative diabetic retinopathy (PDR) who either failed to respond to panretinal photocoagulation or experienced recurrence. After a single dose of bevacizumab, complete resolution occurred in 78.8 percent at one month, 63.6 percent at three months, and 45.4 percent at six months. After a second injection in the third month, the complete resolution rate increased to 60.6 percent in the sixth month. Visual acuity increased (20/225 to 20/108), macular edema decreased (11.65 mm³ to 8.92 mm³) and no complications were observed.