Courtesy of Amani Fawzi, MD.
Peripheral retinal manifestations of hydroxychloroquine toxicity in Asian patients. A, Fundus autofluorescence (FAF) shows hyperautofluorescence along the inferior arcade in both eyes. B, OCT scan through the right fovea (left) shows disruption of the outer retina and loss of the ellipsoid zone temporal to the optic nerve. More inferior scans (right) highlight the extension of this loss along the inferior arcade. This photoreceptor loss explains the unmasking of the retinal pigment epithelium (RPE) autofluorescence and relative hyperautofluorescence in this region. C, 30-2 HVF illustrates the peripheral localization of the visual field defects, which would be missed on 10-2 HVF.