Moderate to severe nonischemic central retinal vein occlusion (CRVO). A, Ultra-wide- field fundus photograph of moderate to severe nonischemic, or perfused, CRVO in an eye with 20/80 vision. Dilated retinal veins and retinal hemorrhages are present in all 4 quadrants. Cotton-wool spots can be seen near the optic nerve head. B, A fluorescein angiography image at 1 minute, 8 seconds reveals relatively intact perfusion of the retinal capillary bed but dilated vessels and peripheral leakage from the large vessels. There are some areas of capillary nonperfusion in the superior macula. C, An SD-OCT scan shows severe cystoid retinal edema with a serous foveal detachment. After 2.5 years of anti-VEGF treatment with bevacizumab, the patient maintains a visual acuity of 20/40.