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  • By Theodore Pasquali, MD
    Refractive Mgmt/Intervention

    This prospective study found that wavefront-guided LASIK can provide an effective and predictable correction of low to moderate myopia in the long term, preserving the patient’s visual acuity and quality.

    As the first large, prospective mid- to-long-term study for wavefront guided treatment, this is an important study. 

    Subjects included 145 consecutive patients (255 eyes) with low to moderate myopia who underwent wavefront-guided LASIK using the VISX CustomVue advanced excimer laser platform (Abbott Medical Optics). 

    UDVA was 20/25 or better in 98 percent and 100 percent of eyes at one and four years, respectively. At four years, only one eye lost a single line of CDVA and only three eyes required enhancements. Manifest sphere was -0.08 D at 1 year and -0.14 D at four years, demonstrating a very small but statistically significant regression. At four years, 97.3 percent of eyes were within 0.50 D of target refraction.

    The authors conclude that future studies with longer follow-up times are necessary to confirm the stability of the outcomes reported here. Such studies should try to elucidate whether the aberrometric optimization achieved with this type of wavefront-guided LASIK treatment provides an advantage in terms of better tolerance to the impact of aberrometric modifications associated with age.