Patients with higher degrees of HOAs benefit more from wavefront-guided OPDCAT

This retrospective study reported on the predictability, efficacy, safety, and stability of custom ablation LASIK using the NIDEK Advanced Vision Excimer Laser System (NAVEX, Nidek Inc., Fremont, Calif.) with the optical path difference custom aspheric treatment (OPDCAT) ablation algorithm in 120 eyes. The results indicated that wavefront-guided OPDCAT with the NAVEX system is safe and effective for treating myopia and yields excellent visual acuity and refractive outcomes. Eyes with greater than 0.3 μm of higher order aberrations preoperatively will benefit more from OPDCAT treatment than eyes with smaller amounts of higher order aberrations.

The average age of patients included in the study was 34 years and ranged from 20 to 61 years. Mean preoperative manifest refraction spherical equivalent was -3.88±2.01 D and ranged from -9.50 to -1.15 D. Mean preoperative sphere was -3.89±1.96 D and ranged from -9.00 to -0.25 D, and mean preoperative cylinder was -0.67±0.71 D and ranged from -4.50 to 0.00 D.

The patients were followed for between six and 18 months. Mean postoperative spherical equivalent refraction was -0.05 D and ranged from -0.92 to +0.88 D. Uncorrected visual acuity was 1 or better in 109 (91 percent) eyes and 1.2 or better in 47 (39 percent) eyes. Postoperative spherical equivalent refraction was within 0.50 D of the intended correction in 110 (92 percent) eyes. Fifty-two (43 percent) eyes gained one or more lines of BSCVA, and no eyes lost more than one line of BSCVA.

Higher order aberrations root-mean-square increased by 0.053 μm postoperatively. Patients with preoperative higher order aberrations of 0.3 μm or greater were less likely to have induced higher order aberrations.

Financial Disclosures
Dr. Stahl is a consultant for AcuFocus, Inc.